JN1168 重组人β2-微球蛋白(B2M)

我公司致力于为客户提供高纯度、低成本的活性重组蛋白，包括重组人β2-微球蛋白(B2M)在内的各类受体、细胞因子、生长因子、转录因子、激素、酶、毒性蛋白、病毒抗原等。...

特别提示：包括重组人β2-微球蛋白(B2M)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人β2-微球蛋白(B2M)
英文名称：Recombinant Human beta-2-Microglobulin
产品货号：JN1168
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Ile21-Met119在N端含有His标签。

B2M质量控制：＞95%(还原性SDS-PAGE)

B2M制剂：冻干品

B2M保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

B2M复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于B2M：
β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecules, involved in the presentation of peptide antigens to the immune system. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Serum B2M concentration is increased in renal diseases, various malignant diseases and some inflammatory and autoimmune disorders. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. B2M has been shown as a marker for monitoring inflammatory disease activity and it appears likely to have a destructive role in amyloidosis-related arthritis. B2M might be involved in the OA (osteoarthritis) pathogenesis. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation. B2M could be a potential therapeutic target in ovarian cancer.

根据您的关注的重组人β2-微球蛋白(B2M)，rbeta-2-Microglobulin，重组beta-2-Microglobulin，rhbeta-2-Microglobulin，重组B2M，Recombinant Human beta-2-Microglobulin，重组β2-微球蛋白，重组人B2M，rB2M，重组人β2-微球蛋白，重组人beta-2-Microglobulin，rhB2M，您可能还对以下产品有需求：



名称：重组人白介素IL-18(白细胞介素18)
货号：JN0383
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Tyr37-Asp193在C端含有His标签。

IL-18/IL-1F4质量控制：＞95%(还原性SDS-PAGE)。

IL-18/IL-1F4制剂：冻干品

IL-18/IL-1F4保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-18/IL-1F4复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-18/IL-1F4：
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells.

关注重组人β2-微球蛋白(B2M)，rbeta-2-Microglobulin，重组beta-2-Microglobulin，rhbeta-2-Microglobulin，重组B2M，Recombinant Human beta-2-Microglobulin，重组β2-微球蛋白，重组人B2M，rB2M，重组人β2-微球蛋白，重组人beta-2-Microglobulin，rhB2M的同时，为您推荐更多您可能感兴趣的产品：

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