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价格:电议
所在地:北京
型号:96T
更新时间:2023-07-06
浏览次数:1756
公司地址:北京市海淀区厢黄旗2号楼1层4-179室
李小姐(女士)
Quidel CICP ELISA Kit An enzyme immunoassay to quantitatively measure C-terminal Propeptide of Type I Collagen (CICP) in Serum .
Quidel CICP ELISA Kit SUMMARY AND EXPLANATION
Collagen, the triple-helical molecule which forms the fi brous framework of all connective tissues, is synthesized as procollagen, a larger precursor molecule. Procollagen consists of mature collagen with extension peptides at both the amino and carboxy termini. These extension peptides, or propeptides, are cleaved from the collagen molecule by specific proteases prior to incorporation of collagen into a growing collagen fibril. The release of these peptides into the circulation provides a stoichiometric representation of the production of collagen.
The MicroVue CICP EIA Kit provides a quantitative method for determining levels of CICP (C-Terminal of Type I Collagen) in serum. Levels of CICP are indicative of collagen production in vivo. As the primary organic constituent of bone, Type I Collagen levels have been linked to bone growth and formation. Elevated levels of CICP have been shown in diseases associated with high levels of bone turnover, including Paget’sdiseasethebonehyperthyroidism, primaryhyperparathyroidism and renal osteodystrophy. In some cases, elevated levels of CICP have also been documented in early menopause. Low levels of CICP have been shown in growth hormone-defi cient children.
Quidel CICP ELISA Kit PRINCIPLE OF THE PROCEDURE
The MicroVue CICP assay is a sandwich enzyme immunoassay in a microtiter plate format utilizing a monoclonal anti-CICP antibody coated on the plate, a rabbit anti-CICP antiserum, a goat anti-rabbit alkaline phosphatase conjugate, and a pNPP substrate to quantify CICP in human serum.
关键词:Quidel公司,Quidel代理商,美国Metre公司,骨代谢试剂盒,CICP ELISA试剂盒
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