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价格:电议
所在地:北京
型号:20ug
更新时间:2023-07-06
浏览次数:1451
公司地址:北京市海淀区厢黄旗2号楼1层4-179室
李小姐(女士)
中文名称
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重组小鼠IL-4 (Animal Free) 20ug 详细介绍:
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英文名称
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Recombinant Murine IL-4
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货号
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AF-214-14
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试剂级别
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细胞培养级
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产地
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美国PeproTech
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别名Synonyms
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BCGF, BCDF, B cell stimulating factor (BSF-1)
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描述Description
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IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 120 amino acid residues. Manufactured using all non-animal reagents.
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