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Human APRIL ELISA Kit

  • 产品/服务:Human APRIL ELISA Kit
  • 型 号:96T
  • 品 牌:美国ebioscience
  • 单 价:面议 
  • 更新日期:2018-12-13
  • 有效期至:长期有效
  • 浏览次数:906
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Human APRIL Platinum ELISA KitBender公司Human APRIL Platinum ELISA Kit Description: The human APRIL ELISA is an enzyme-l...

产品详细介绍
Human APRIL Platinum ELISA Kit Bender公司


Human APRIL Platinum ELISA Kit 
Description: The human APRIL ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of human APRIL. The human APRIL ELISA is for research use only. Not for diagnostic or therapeutic procedures.


APRIL (A Proliferation-Inducing Ligand) is a member of the tumor necrosis factor family. APRIL shows high levels of expression in tumors of different origin and low level of expression in normal cells. APRIL shares two TNF receptor family members, TACI and BCMA with another TNF homolog, BlyS/BAFF both of which have been reported to play a role in autoimmune disease and cancer. APRIL appears to play a role in T-independent type II antigen responses and T cell survival, but can also induce proliferation/survival of non lymphoid cells. Local production of APRIL was found in arthritic joints of patients with inflammatory arthritis. Biologically active BlyS/BAFF and APRIL heterotrimers are expressed in patients with systemic immune based rheumatic diseases. A soluble form of the high affinity BCMA receptor has been shown to inhibit the proliferative activity of APRIL in vitro, thus decreasing tumor cell proliferation, while APRIL-transfected cells show an increased rate of tumor growth very directly, suggesting that APRIL is implicated in the regulation of tumor cell growth.

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