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价格:电议
所在地:北京
型号:10ug
更新时间:2023-07-06
浏览次数:817
公司地址:北京市海淀区厢黄旗2号楼1层4-179室
李小姐(女士)
中文名称
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重组人PDGF-BB (Animal Free) 10ug详细介绍:
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英文名称
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Recombinant Human PDGF-BB
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货号
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AF-100-14B
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试剂级别
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细胞培养级
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产地
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美国PeproTechHuman PDGF-BB报价
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别名Synonyms
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Platelet-Derived Growth Factor-BB, Glioma-derived growth factor (GDGF), Osteosarcoma-derived Growth Factor (ODGF)
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描述Description
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PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids). Manufactured using all non-animal reagents.
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