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价格:电议
所在地:北京
型号:10ug
更新时间:2023-07-06
浏览次数:1083
公司地址:北京市海淀区厢黄旗2号楼1层4-179室
李小姐(女士)
中文名称
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Recombinant Human BDNF详细介绍:
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英文名称
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Recombinant Human BDNF
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货号
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AF-450-02
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试剂级别
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细胞培养级
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产地
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美国PeproTech
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别名Synonyms
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Brain Derived Neurotrophic Factor
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描述Description
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BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0 kDa homodimer of two 119 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical.
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