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96T Human APRIL ELISA Kit

北京科瑞美科技有限公司
会员指数: 企业认证:    

价格: 电议

所在地:北京

型号:96T

更新时间:2019-05-21

浏览次数:985

公司地址:北京市海淀区厢黄旗2号楼1层4-179室

李小姐(女士)  

产品简介

Human APRIL Platinum ELISA KitBender公司Human APRIL Platinum ELISA Kit Description: The human APRIL ELISA is an enzyme-l

公司简介

北京科瑞美科技有限公司是一家专门从事临床实验室产品销售及售后服务的高新技术企业。经过几年的不懈努力,以及广大用户的肯定与支持,已成为国内一流的生物试剂和仪器供应商。

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产品说明

Human APRIL Platinum ELISA Kit Bender公司


Human APRIL Platinum ELISA Kit 
Description: The human APRIL ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of human APRIL. The human APRIL ELISA is for research use only. Not for diagnostic or therapeutic procedures.


APRIL (A Proliferation-Inducing Ligand) is a member of the tumor necrosis factor family. APRIL shows high levels of expression in tumors of different origin and low level of expression in normal cells. APRIL shares two TNF receptor family members, TACI and BCMA with another TNF homolog, BlyS/BAFF both of which have been reported to play a role in autoimmune disease and cancer. APRIL appears to play a role in T-independent type II antigen responses and T cell survival, but can also induce proliferation/survival of non lymphoid cells. Local production of APRIL was found in arthritic joints of patients with inflammatory arthritis. Biologically active BlyS/BAFF and APRIL heterotrimers are expressed in patients with systemic immune based rheumatic diseases. A soluble form of the high affinity BCMA receptor has been shown to inhibit the proliferative activity of APRIL in vitro, thus decreasing tumor cell proliferation, while APRIL-transfected cells show an increased rate of tumor growth very directly, suggesting that APRIL is implicated in the regulation of tumor cell growth.

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