特别提示:包括重组小鼠CD40(TNFRSF5)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组小鼠CD40(TNFRSF5)
英文名称:Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 5
产品货号:JN0512
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu20-Arg193在C端含有His标签。
CD40/TNFRSF5质量控制:>95%(还原性SDS-PAGE)
CD40/TNFRSF5制剂:冻干品
CD40/TNFRSF5保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
CD40/TNFRSF5复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于CD40/TNFRSF5:
CD40 is a Type I Transmembrane Glycoprotein that belo
ngs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic compo
nents to initiate signaling pathways. Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction. CD40 plays an essential role in mediating a broad variety of immune and inflammatory respo
nses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
根据您的关注的
重组小鼠CD40(TNFRSF5),rmTNFRSF5,rmCD40,重组Tumor Necrosis Factor Receptor Superfamily Member 5,重组小鼠CD40,rTNFRSF5,rCD40,重组小鼠Tumor Necrosis Factor Receptor Superfamily Member 5,重组TNFRSF5,Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 5,重组CD40,重组小鼠TNFRSF5,您可能还对以下产品有需求:
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关注
重组小鼠CD40(TNFRSF5),rmTNFRSF5,rmCD40,重组Tumor Necrosis Factor Receptor Superfamily Member 5,重组小鼠CD40,rTNFRSF5,rCD40,重组小鼠Tumor Necrosis Factor Receptor Superfamily Member 5,重组TNFRSF5,Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 5,重组CD40,重组小鼠TNFRSF5的同时,为您推荐更多您可能感兴趣的产品:
名称:重组人MYDGF
货号:JN0384
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Ser33-Leu173在N端含有His标签
MYDGF/C19orf10质量控制:>95%(还原性SDS-PAGE)。
MYDGF/C19orf10制剂:冻干品
MYDGF/C19orf10保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
MYDGF/C19orf10复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于MYDGF/C19orf10:
Myeloid-derived growth factor (MYDGF) is a secreted protein which belo
ngs to the UPF0556 family. MYDGF was stro
ngly expressed in spleen, prostate and lung, and weakly expressed in the left ventricle and liver. Bone marrow-derived mo
nocyte and paracrine-acting protein promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). MYDGF stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. It inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. MYDGF is involved in endothelial cell proliferation and angiogenesis. It may serve as a prototypical example for the development of protein-ba
sed therapies for ischemic tissue repair.
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