JN0607 重组人氧化型低密度脂蛋白受体1

我公司致力于为客户提供高纯度、低成本的活性重组蛋白，包括重组人氧化型低密度脂蛋白受体1在内的各类受体、细胞因子、生长因子、转录因子、激素、酶、毒性蛋白、病毒抗原等。

北京百奥莱博科技有限公司是一家专业的生物试剂销售公司。公司主要经营血清、抗原、抗体等生物试剂产品，可以为您提供专业的技术服务，以优良的价格、优质的服务、优先的理念，满足客户的各方面的需求，与国内多家企业、单位建立了良好的长期合作关系，拥有较好的企业信誉和品牌形象。 主营产品:血清、抗体、抗原、核酸提取、核酸纯化等生化试剂

特别提示：包括重组人氧化型低密度脂蛋白受体1(OLR1)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人氧化型低密度脂蛋白受体1(OLR1)
英文名称：Recombinant Human Oxidized Low-Density Lipoprotein Receptor 1
产品货号：JN0607
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser61-Gln273在C端含有His标签。

OLR1质量控制：＞95%(还原性SDS-PAGE)

OLR1制剂：冻干品

OLR1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

OLR1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于OLR1：
Oxidized Low-Density Lipoprotein Receptor 1 (Ox-LDL Receptor 1) is a secreted, single-pass type II membrane protein which belongs to the C-type lectin superfamily. Ox-LDL Receptor 1 is expressed at high levels in endothelial cells and vascular-rich organs such as placenta, lung, liver, brain, aortic intima, bone marrow, spinal cord and substantia nigra. The expression of Ox-LDL Receptor 1 is induced by inflammatory cytokines such as TNF, IFNG and IL6 by pathological conditions, such as hyperlipidemia, hypertension and diabetes mellitus. Ox-LDL Receptor 1 mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (OxLDL) by vascular endothelial cells. Ox-LDL Receptor 1 association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. Ox-LDL Receptor 1 also binds to oxLDL, which acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. It also participates in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation.

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关注重组人氧化型低密度脂蛋白受体1(OLR1)，重组人Oxidized Low-Density Lipoprotein Receptor 1，重组OLR1，Recombinant Human Oxidized Low-Density Lipoprotein Receptor 1，重组人氧化型低密度脂蛋白受体1，重组Oxidized Low-Density Lipoprotein Receptor 1，rhOLR1，rOLR1，重组人OLR1，重组氧化型低密度脂蛋白受体1的同时，为您推荐更多您可能感兴趣的产品：


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